Synthesis of Bridged Steroids. VI. B-Norsteroids having a Gibbane B-C-D Ring System. (1). Synthesis of 5-Cyano-B-norsteroids via Hydrocyanation
スポンサーリンク
概要
- 論文の詳細を見る
B-Nor-⊿^4-3-ketosteroids such as compounds (11a, 11b, 11c, 17a, 17b and 23) were synthesized starting from ⊿^5-3β-hydroxysteroids. Hydrocyanation of these enones was investigated and by treatment with diethylaluminum cyanide only the 5β-vinyl derivatives (17a, 17b and 23) gave successfully the corresponding 3-keto-5β-cyano compounds (18a, 18b, and 24a), intermediates necessary for the synthesis of B-norsteroids having cis-bicyclo [3,2,1] octane ring system.
- 社団法人日本薬学会の論文
- 1971-08-25
著者
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村上 正行
Shionogi Research Laboratory Shionogi & Co. Ltd.
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永田 亘
Shionogi Research Laboratory, Shionogi & Co., Ltd.
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成定 昌幸
Shionogi Research Laboratory, Shionogi & Co., Ltd.
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早瀬 善男
Shionogi Research Laboratory, Shionogi & Co., Ltd.
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永田 亘
塩野義製薬株式会社研究所
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永田 亘
Shionogi Research Laboratories Shionogi & Co. Ltd.
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成定 昌幸
塩野義製薬株式会社研究所
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若林 利生
Shionogi Research Laboratory
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早瀬 善男
Shionogi Research Laboratory Shionogi & Co. Ltd.
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若林 利生
Shionogi Research Laboratory:(present Address)central Research Institute Teijin Limited
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早瀬 善男
Shionogi And Co. Ltd. Shiga Jpn
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