39 dl-ジベレリンA_<15>の立体選択的全合成に於る問題点

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概要

• 論文の詳細を見る

• Starting from the tetracyclic enone 1, the key intermediate for our total synthesis of diterpene alkaloids, we have succeeded in the first stereo-controlled total synthesis of dl-gibberellin A_<15> (dl-GA_<15>). A general synthetic plan which we envisaged for the total synthesis of dl-GA_<15> is presented. Difficulties and conspicuous features encountered in carrying out this plan are discussed in terms of the following; (1) B-ring contraction, (2) hydrocyanation, (3) two-carbon homologation, (4) selective ozonization, (5) a new cyclization, (6) selective alkylation, and (7) demethylation.

• 天然有機化合物討論会の論文
• 1970-10-01

著者

• 鎌田 進

  塩野義研

• 永田 亘

  塩野義製薬株式会社研究所

• 成定 昌幸

  塩野義製薬株式会社研究所

• 永田 亘

  塩野義研

• 若林 利生

  塩野義研

• 成定 昌幸

  塩野義研

• 早瀬 善男

  塩野義研

• 早瀬 善男

  Shionogi Research Laboratory Shionogi & Co. Ltd.

• 若林 利生

  Shionogi Research Laboratory:(present Address)central Research Institute Teijin Limited

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