The Isolation of New Pyrano-2-arylbenzofuran Derivatives from the Root of Glycyrrhiza glabra

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概要

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• Two new pyrano-2-arylbenzofuran derivatives named glabrocoumarones A and B were isolated from commercially available licorice of Glycyrrhiza glabra origin, and thier structures were elucidated as 4'-6-dihydroxy-[6", 6"-dimethylpyrano(2", 3" : 2', 3')]-2-arylbenzofuran and 2', 6-dihydroxy-[6", 6"-dimethylpyrano(2", 3" : 4', 3')]-2-aryl-benzofuran, respectively, on the basis of spectroscopic evidence. Six known compounds were also obtained and identified spectroscopically as glabrol, 3-hydroxygrabrol, shinflavanone, [6", 6"-dimethylpyrano(2", 3" : 7,8)]-[6''', 6'''-dimethylpyrano(2''', 3''' : 4', 3')]-flavanone (xambioona), 3,3'-di-γ, γ-dimethylallyl-2'-4,4'-trihydroxychalcone and [6", 6"-dimethylpyrano(2", 3" : 4,5)]-3'-γ, γ-dimethylallyl-2', 3,4'-trihydroxychalcone.

• 公益社団法人日本薬学会の論文
• 1996-06-15

著者

• Kinoshita Takeshi

  東京薬科大学 薬学部

• Mizutani Kenji

  丸善製薬

• Mizutani Kenji

  Research Laboratory Maruzen Pharmaceuticals Co. Ltd.

• HIRAGA Yukio

  Meiji College of Pharmacy

• Tamura Yukiyoshi

  Research Laboratories, Maruzen Pharmaceuticals Co., Ltd.

• KINOSHITA Takeshi

  Faculty of Pharmaceutical Sciences, Teikyo University

• Hiraga Yukio

  Meiji College Of Pharamacy At Setagaya

• Takahashi Kunio

  Meiji Pharmaceutical University

• Tamura Yukiyoshi

  Research Laboratory Maruzen Pharmaceuticals Co. Ltd.

• Tamura Yukiyoshi

  Research Laboratories Maruzen Pharmaceuticals Co. Ltd.

• KAJIYAMA Kiichiro

  Meiji College of Pharmacy at Setagaya

• Kajiyama K

  Meiji College Of Pharmacy At Setagaya

• Kinoshita Takeshi

  Faculty Of Engineering Yamaguchi University

• Mizutani Kenji

  Research Center Maruzen Pharmaceuticals Co. Ltd.

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