A NOVEL AND CHIRAL SYNTHESIS OF BOTH ENANTIOMERS OF TRANS-3-AMINO-4-HYDROXYHEXAHYDROAZEPINE, A KEY INTERMEDIATE FOR THE SYNTHESIS OF BALANOL
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概要
- 論文の詳細を見る
Both enantiomers of the hexahydroazepine (7), key intermediates for the synthesis of (-)-balanol (1) and its enantiomer, were effectively synthesized via the shortest route involving stannyl radical cyclization of the aldehyde (4) connected with oxime ether followed by the optical resolution of the resulting azepine (7).
- 公益社団法人日本薬学会の論文
- 1996-03-15
著者
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NAITO Takeaki
Kobe Pharmaceutical University
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Naito T
Kobe Pharmaceutical University
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Naito Takeaki
Kobe Pharmaceutical Univ.
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Ninomiya I
Kobe Pharmaceutical University Motoyamakita
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Kiguchi T
Kyushu Univ. Fukuoka Jpn
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NINOMIYA Ichiya
Kobe Pharmaceutical University
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KIGUCHI Toshiko
Kobe Pharmaceutical University, Motoyamakita
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TORIEDA Mayumi
Kobe Pharmaceutical University
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TAJIRI Kazumi
Kobe Pharmaceutical University
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- A NOVEL AND CHIRAL SYNTHESIS OF BOTH ENANTIOMERS OF TRANS-3-AMINO-4-HYDROXYHEXAHYDROAZEPINE, A KEY INTERMEDIATE FOR THE SYNTHESIS OF BALANOL
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