Palladium-Catalyzed Cross Coupling Reaction of N-Alkoxyimidoyl Bromides and Its Application to One-Pot Synthesis of N-Arylamines
スポンサーリンク
概要
- 論文の詳細を見る
The synthetic utility of N-alkoxyimidoyl halides is demonstrated using the palladium-catalyzed cross-coupling reaction. The Sonogashira and Suzuki–Miyaura coupling reactions of N-alkoxyimidoyl bromides produced versatile ketoxime ethers in good to excellent yields. A one-pot reaction of the imidoyl bromides with arylboronic acid and allylmagnesium bromide to produce N-arylamines via Suzuki–Miyaura coupling followed by domino reaction involving sequential addition-eliminative rearrangement-addition reactions was developed.
著者
-
Naito Takeaki
Kobe Pharmaceutical Univ.
-
Ueda Masafumi
Kobe Pharmaceutical University
-
Miyata Okiko
Kobe Pharmaceutical Univ.
-
Ikeda Yuki
Kobe Pharmaceutical University
-
Ito Yuta
Kobe Pharmaceutical University
-
Miyoshi Tetsuya
Kobe Pharmaceutical University
-
Sugita Shoichi
Kobe Pharmaceutical University
-
Aoi Naoki
Kobe Pharmaceutical University
-
Sato Aoi
Kobe Pharmaceutical University
関連論文
- Solid-Phase Tandem Radical Addition-Cyclization Reaction : Triethylborane-Induced Reaction of Oxime Ethers Anchored to Polymer Support
- Stannyl Radical Addition-Cyclization of Oxime Ethers Connected with Olefins
- Radical Cyclization in Heterocycle Synthesis. II. Total Synthesis of (±)-Anantine and (±)-Isoanatine
- DIASTEREOSELECTIVE SYNTHESIS OF TRIACETYL-L-erythro-C18-SPHINGOSINE
- P-449 SYNTHESIS OF NATURAL BENZOFURANS BY REAGENT-CONTROLLED DOMINO REACTION
- P-219 TOTAL SYNTHESIS OF PENMACRIC ACID AND ITS STEREOISOMERS
- Heterocycle Synthesis via Radical Addition-Cyclization of Oxime Ethers
- Radical Cyclization in Heterocycle Synthesis.12. Sulfanyl Radical Addition-Addition-Cyclization(SRAAC) of Unbranched Diynes and Its Application to the Synthesis of A-Ring Fragment of 1α, 25-Dihydroxyvitamin D_3
- P-439 FORMAL SYNTHESIS OF MARTINELLINES VIA RADICAL ADDITION-CYCLIZATION-ELIMINATION REACTION
- Radical Cyclization in Heterocycle Synthesis 15 : Relationship between a Radical Species and Radical Acceptors of Three Different Types of Double Bond in Radical Addition-Cyclization
- Stereoselective Synthesis of β-Hydroxyphenylalanines Using Imino 1, 2-Wittig Rearrangement of Hydroximates
- Synthesis of (±)-Pseudodistomins A and B Acetates
- HYDROXIMATE AS A SYNTHETICALLY USEFUL FUNCTIONAL GROUP Part II : SYNTHESIS OF (±)-OXO-PARABENZLACTONE
- A NOVEL SYNTHESIS OF (+)-AZIMIC ACID
- A NOVEL AND CHIRAL SYNTHESIS OF BOTH ENANTIOMERS OF TRANS-3-AMINO-4-HYDROXYHEXAHYDROAZEPINE, A KEY INTERMEDIATE FOR THE SYNTHESIS OF BALANOL
- Synthesis of Aminocyclohexitol via Carbon-Carbon Bond-Forming Radical Cyclization of Oxime Ether
- Diastereoselective Solid-Phase Radical Addition to Oxime Ether Anchored to Polymer Support
- Development of New Synthetic Reactions for Nitrogen-Containing Compounds and Their Application
- Palladium-Catalyzed Cross Coupling Reaction of N-Alkoxyimidoyl Bromides and Its Application to One-Pot Synthesis of N-Arylamines
- α-Heteroarylation of Ketones via the Umpolung Reaction of N-Alkoxyenamine