Formal [3+2] Cycloaddition Reactions of 1-Methyl-2-[methylthio-(trimethylsilylmethylimino)methylimino]-1,2-dihydropyridine and Related Compound with Carbonyl Compounds Promoted by Fluoride Ion
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概要
- 論文の詳細を見る
Reaction of 1-methyl-2-[methylthio(trimethylsilylmethylimino)methylimino]-1,2-dihydropyridine (1), prepared from 2-amino-1-methyl-pyridinium iodide in 3 steps, with carbonyl compounds in the presence of 2 eq of cesium fluoride in acetonitrile afforded 2-(1-methyl-1,2-dihydropyridylidene)aminooxazoline derivatives (12), which correspond to formal [3+2] cycloadducts of the aminonitrile ylid. Further, compound 1 reacted with carbonyl compounds in the presence of a catalytic amount of tetra-n-butylammonium fluoride (TBAF) to give corresponding cycloadducts.
- 公益社団法人日本薬学会の論文
- 1995-02-15
著者
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富永 義則
Faculty of Pharmaceutical Sciences, Nagasaki University
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高良 真也
Faculty of Pharmaceutical Sciences, Nagasaki University
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高良 真也
Faculty Of Liberal Arts Nagasaki University
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富永 義則
Faculty Of Pharmaceutical Sciences
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富永 義則
Faculty Of Pharmaceutical Sciences Nagasaki University
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上江田 一雄
Faculty of Liberal Arts, Nagasaki University
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上江田 一雄
Faculty Of Liberal Arts Nagasaki University
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