Improved Procedure for N-Formylation of Amines to Formamides Using Formic Acid, Oxalyl Chloride and Imidazole
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概要
- 論文の詳細を見る
The reaction of imidazole (15) with formyl chloride (14), generated in situ by the action of oxalyl chloride (10) on formic acid (3), afforded N-formylimidazole (7), which is a convenient formylating reagent. This procedure was used to prepare N-formyl derivatives (2) of aliphatic, aromatic and heteroaromatic amines (1) under mild conditions.
- 公益社団法人日本薬学会の論文
- 1994-09-15
著者
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北川 徳治郎
Faculty of Pharmaceutical Sciences
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北川 徳治郎
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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伊藤 淳子
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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筒井 千夏
Faculty of Pharmaceutical Sciences, Kobe Gakuin University
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伊藤 淳子
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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筒井 千夏
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
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