Synthesis of Artificial Glycoconjugates of Arginine-Vasopressin and Their Antidiuretic Activities
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概要
- 論文の詳細を見る
Argiine-vasopressin (AVP) derivatives modified at the glutamine side chain amide with carbohydrate via an alkylene spacer (1a-d) were synthesized from new glycosylated glutamine derivatives (3a-d) by solid-phase synthesis. Glycoconjugates of AVP modified at the C-terminal amide (2a-d) were also synthesized from vasopressionic acid. All of them exhibited antidiuretic activity.
- 社団法人日本薬学会の論文
- 1994-10-15
著者
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山田 治民
Drug Delivery System Institute, Ltd., Bldg. of Research Institute for Biosciences, The Science Unive
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山田 治民
(株) ディ・ディ・エス研究所
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鈴木 幸吉
(株) ディ・ディ・エス研究所
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洲崎 浩
(株) ディ・ディ・エス研究所
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渡辺 宏
(株) ディ・ディ・エス研究所
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洲崎 浩
Drug Delivery System Institute, Ltd.,
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鈴木 幸吉
Drug Delivery Systme Institute, Ltd.,
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池田 政浩
Drug Delivery System Institute, Ltd.,
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渡辺 宏
Drug Delivery System Institute, Ltd.,
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洲崎 浩
Drug Delivery System Institute Ltd.
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Yamada H
Yamada Apiculture Center Inc.
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池田 政浩
Drug Delivery System Institute Ltd.
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Yamada H
School Of Science And Technology Kwansei Gakuin University
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Yamada Harutami
Drug Delivery System Institute Ltd.:(present Address)tanabe Seiyaku Co. Ltd.
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