Fluorometric Determination of Acetaminophen and Its Conjugates in Whole Blood
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概要
- 論文の詳細を見る
A fluorometric procedure has been developed for the determination of acetaminophen and its conjugates, not only in blood plasma and serum, but also in whole blood. This method, in principle, is based on a method reported previously for the determination of acetaminophen in preparations, in which the drug is oxidized with potassium ferricyanide to give a fluorescent substance. The present method has the advantage of being able to determine the drug without hydrolysis to p-aminophenol, in contrast to many of the published methods. The detection limit is about 4μg/ml of acetaminophen in whole blood, which is comparable to that of spectrophotometric assays reported previously.
- 社団法人日本薬学会の論文
- 1980-02-25
著者
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柴崎 寿一郎
Faculty Of Pharmaceutical Sciences Nagasaki University
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小西 良士
帝國製薬(株)研究開発本部
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小西 良士
Faculty of Pharmaceutical Sciences, Nagasaki University
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山田 敬二
Faculty of Pharmaceutical Sciences, Nagasaki University
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山田 敬二
Faculty Of Pharmaceutical Sciences Nagasaki University
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