Pyridoxamine Analogs. III. Molecular Species protonated and methylated on the Pyridine Nitrogen

概要

論文の詳細を見る
To know the absorption spectra associated with species protonated and nonprotonated on the pyridine nitrogen of pyridoxamine and its analogs, spectra of methanol solutions of the following four compounds were examined ; pyridoxamine (I), 3-hydroxy-4-aminomethylpyridine (II), 1-methylpyridoxamine chloride (III), and 1-methyl-3-hydroxy-4-aminomethylpyridinium chloride (IV). Assignments of the absorption bands to molecular species present in methanol solutions are summarized in Table I. Similarities of spectral characteristics of N-protonated and N-methylated species were shown by comparison of the spectra of the compounds. On the basis of the absorption bands assigned to Zn (II), Cu (II) and Ni (II) chelate of III and IV (Table II), the presence of N-protonated species of metal chelates of I and II in acidic methanol and their spectra are discussed (Table III).
公益社団法人日本薬学会の論文
1975-08-25