Isolation and Structure of Two Metabolites of a Macrolide Antibiotic, SF-837 Substance

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概要

• 論文の詳細を見る

• M_1 Substance, one of the main metabolites of SF-837,was isolated from the urine of rats, or digested solution of SF-837 with a liver homogenate, and identified as 4"-depropionyl SF-837 by direct comparison. Another major metabolite, M_2 substance was isolated from the bile of rats, and its structure was proposed to be 14-hydroxyl M_1 on the basis of the mass and nuclear magnetic resonance analyses.

• 社団法人日本薬学会の論文
• 1972-11-25

著者

• 梅村 甲子郎

  東邦大学 薬学部

• 梅村 甲子郎

  東邦大学薬学部

• 梅村 甲子郎

  日立製作所中央研究所

• 梅村 甲子郎

  東邦大薬

• 庄村 知子

  Central Research Laboratories, Meiji Seika Kaisha, Ltd.

• 梅村 甲子郎

  Central Research Laboratories, Meiji Seika Kaisha, Ltd.

• 井上 重治

  Central Research Laboratories, Meiji Seika Kaisha, Ltd.

• 鶴岡 崇士

  Central Research Laboratories, Meiji Seika Kaisha, Ltd.

• 尾本 捷二

  Central Research Laboratories, Meiji Seika Kaisha, Ltd.

• 仁井田 太郎

  Central Research Laboratories, Meiji Seika Kaisha, Ltd.

• 鶴岡 崇士

  明菓・中研

• 仁井田 太郎

  Central Research Laboratories Meiji Seika Kaisha Ltd.

• 庄村 知子

  Central Research Laboratories Meiji Seika Kaisha Ltd.

• 尾本 捷二

  Central Research Laboratories Meiji Seika Kaisha Ltd.

• 井上 重治

  Central Research Laboratories Meiji Seika Kaisha Ltd.

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