Nuclear Magnetic Resonance Spectroscopy of Amino-sugars. I. Conformation of Methyl 1 3,6-Diamino-3,6-dideoxy-α-D-altropyranoside and Its Derivatives
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概要
- 論文の詳細を見る
Conformations of four 3,6-disubstituted derivatives of methyl α-D-altropyranoside in various solvents were studied by nuclear magnetic resonance spectroscopy. The derivatives examined included methyl 3,6-diamino-3,6-dideoxy-α-D-altropyranoside (I), its di-N-acetate (II), tetar-O, N-acetate (III) and methyl 3,6-diazido-3,6-dideoxy-α-D-altropyranoside (IV). Analysis of the spectra revealed that the predominant conformation in all the cases was C1,but I and II in deuterium oxide were shown to exist partly in the 1C conformation. IV in deuteriochloroform existed probably in a mixture of three conformers. Infrared spectroscopy indicated that the conformers of IV in inert solvents existed in the intramolecularly hydrogen bonded forms. The resonance data of methyl 6-azido-6-deoxy-2-O-methanesulfonyl-α-D-glucopyranoside (X) and methyl 2,6-di-O-methanesulfonyl-α-D-glucopyranoside (XI) were added.
- 公益社団法人日本薬学会の論文
- 1966-10-25
著者
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井上 重治
Central Research Laboratories, Meiji Seika Kaisha, Ltd.
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井上 重治
Central Research Laboratories Meiji Seika Kaisha Ltd.
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