Pyrimidine Nucleosides. II. The Synthesis of Unnatural Pyrimidine Nucleosides saturated at 5,6-Double Bond
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概要
- 論文の詳細を見る
5,6-Dihydroxy-5,6-dihydro-2'-deoxyuridine (IIIa) and 5,6-dihydroxy-5,6-dihydrouridine (IIIb) were prepared via bromination of 2'-deoxyuridine (Ia) and uridine (Ib) respectively, followed by refluxing these unstable intermediates in the neutral conditions to replace the bromo group with the hydroxyl group. In the case of cytidine, however, the 5,6-dihydroxy-5,6-dihydro compound was not obtained by the same procedure as used for preparation of IIIa and IIIb from Ia and Ib.
- 公益社団法人日本薬学会の論文
- 1969-04-25
著者
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金井 貞
Research Labolatories, Kohjin Co., Ltd.
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市野 元信
Research Laboratories, Kohjin Co., Ltd.
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金井 貞
Research Labolatories Kohjin Co. Ltd.
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市野 元信
Research Laboratories Kohjin Company Ltd.:(present Address)kitasato Biochemical Laboratories Bristol
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小嶋 孝司
Research Laboratory, Division of Fermentation & Chemical Products, Kokoku Rayon & Pulp Co., Ltd.
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小嶋 孝司
Research Laboratory Division Of Fermentation & Chemical Products Kokoku Rayon & Pulp Co. Ltd
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- Specific Inhibition of DNA Synthesis by Cyclocytidine
- Syntheses of 1-(5'-Amino-5'-deoxy-β-D-xylofuranosyl) uracil and Its N_3-Methyl Derivative
- Distribution of Cyclocytidine in Tissues
- Autoradiographic Study on the Distribution of Cyclocytidine in Mice
- Studies on the Vilsmeier-Haack Reaction. III. Synthesis of Cytidine Diphosphate Choline
- Studies on the Structure of a New Type of Cyclonucleoside, 6,2'-Triazacyclocytidine
- Reaction of Pyrimidine Nucleosides with Sulfuryl Chloride
- Alteration of 5-Chloropyrimidine Nucleosides in Alkaline Media
- Platelet Aggregation Inhibitors. V. Pyrimidine Derivatives, Indole Derivatives, Benzothiophenes, and Benzoquinolizine Derivative
- Effect of Plasma pH on Stability and Capacity of Aggregation of Platelets
- Synthesis of a Nucleotide Coenzyme, CDP-Choline
- Reactions of Methyl Iodide on 2,2'-Anhydro-1-(β-D-arabinofuranosyl)-uracil and 2,3'-Anhydro-1-(β-D-xylofuranosyl) uracil
- Pyrimidine Nucleosides. III. Reaction of Cytidine or N^4-Acetylcytidine with Partially Hydrolyzed Phosphorus Oxychloride
- Pyrimidine Nucleosides. II. The Synthesis of Unnatural Pyrimidine Nucleosides saturated at 5,6-Double Bond
- Pyrimidine Nucleosides. I. The Convenient Synthesis of 1-β-D-Lyxofuranosylcytosine from Cytidine