Studies on Vitamin B_1 and Related Compounds. CVI. A Novel Synthesis of Hydroxyethylthiamine
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概要
- 論文の詳細を見る
A dihydrothiamine derivative (VI) was prepared by the reaction of IV, V and methylglyoxal. On treatment with hydrochloric acid VI underwent hydrolysis in the presence of water, but in non-aqueous solutions thiamine was afforded under room temperature. Treatment of VI, however, with weak acids such as phosphoric acid, formic acid or acetic acid effected the conversion to hydroxyethylthiamine in fairly good yields.
- 公益社団法人日本薬学会の論文
- 1967-01-25
著者
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吉岡 晃一
Research And Development Division Takeda Chemical Industries Ltd.
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岡 良和
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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平野 弘
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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吉岡 晃一
Chemical Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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岡 良和
Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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平野 弘
Chemical Research Laboratories Central Research Division Takeda Chemical Industries Ltd.
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平野 弘
Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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