Studies on Vitamin B_1 and Related Compounds.CVII.Synthesis of Hydroxyethylthiamine Homologs
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概要
- 論文の詳細を見る
Two types of dihydrothiamine derivatives, IV, VI, VIII, and V, VII, IX, were obtained by the reaction of I, II, and phenylglyoxal derivatives. On treatment with mineral acids both of those underwent hydrolysis in the presence of water, but in non-aqueous solutions thiamine was afforded under room temperature. Treatments of them with weak acids such as phosphoric acid, formic acid and acetic acid effected the conversion to the aryl homologs of hydroxyethylthiamine, XI, XII and XIII.
- 社団法人日本薬学会の論文
- 1967-04-25
著者
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岡 良和
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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平野 弘
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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今宮 栄光
武田薬品工業株式会社研究開発本部化学研究所
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今宮 栄光
Chemical Research Laboratories Central Research Division Takeda Chemical Industries Ltd.
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岡 良和
Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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平野 弘
Chemical Research Laboratories Central Research Division Takeda Chemical Industries Ltd.
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平野 弘
Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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