Urinary Metabolites of Genistein Administered Orally to Rats

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概要

• 論文の詳細を見る

• In a study on the metabolism of flavonoids, the isoflavone genistein was administered orally to rats. Urine samples were collected and treated with β-glucuronidase and arylsulfatase. Genistein and its metabolites, 4', 5, 7-trihydroxyisoflavanone (M1), 4', 7-dihydroxyisoflavan (M2), and p-ethylphenol (M3) were isolated from the urine following treatment with enzymes. The structures of M1, M2, and M3 were determined on the basis of chemical and spectral data.

• 公益社団法人日本薬学会の論文
• 2001-11-01

著者

• Ueda J

  National Institute Of Radiological Sciences

• Ueda J

  Department Of Phytochemistry Tohoku Pharmaceutical University

• OHSAWA Keisuke

  Department of Phytochemistry, Tohoku Pharmaceutical University

• YASUDA Takaaki

  Tohoku Pharmaceutical University

• UEDA Joji

  Tohoku Pharmaceutical University

• OHSAWA Keisuke

  Tohoku Pharmaceutical University

• Ohsawa K

  Department Of Phytochemistry Tohoku Pharmaceutical University

• Ohsawa Keisuke

  Tohoku College Of Pharmacy

• Yasuda T

  Department Of Phytochemistry Tohoku Pharmaceutical University

• Yasuda Takaaki

  Tohoku College Of Pharmacy

• 安田 高明

  Department Of Phytochemistry Tohoku Pharmaceutical University

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