Quantitative Analysis of Cannabinoids from Cannabis sativa Using ^1H-NMR
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概要
- 論文の詳細を見る
A ^1H-NMR method has been developed for the quantitative analysis of pure cannabinoids and for cannabinoids present in Cannabis sativa plant material without any chromatographic purification. The experiment was performed by the analysis of singlets in the range of δ4.0-7.0 in the ^1H-NMR spectrum, in which distinguishable signals of each cannabinoid are shown. Quantitation was performed by calculating the relative ratio of the peak area of selected proton signals of the target compounds to the known amount of the internal standard, anthracene. For this method no reference compounds are needed. It allows rapid and simple quantitation of cannabinoids with a final analysis time of only 5 min without the need for a pre-purification step.
- 公益社団法人日本薬学会の論文
- 2004-06-01
著者
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Choi Young
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yonsei University College
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Choi Y
Leiden Univ. Leiden Nld
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Choi Young
Division Of Functional Genomics Jichi Medical University
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VERPOORTE Robert
Division of Pharmacognosy, Leiden/Amsterdam Center for Drug Research, Gorlaeus Laboratories
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Choi Y
Division Of Pharmacognosy Institute Of Biology Leiden University
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HAZEKAMP Arno
Division of Pharmacognosy, Institute of Biology, Leiden University
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Verpoorte R
Leiden Univ. Leiden Nld
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Verpoorte Robert
Division Of Pharmacognosy Center For Bio-pharmaceutical Sciences Leiden University
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Hazekamp Arno
Division Of Pharmacognosy Institute Of Biology Leiden University
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