Dianion of Sulfinylacetone as a Synthetic Equivalent of β-Enolate of Propionic Acid: A Novel Synthesis of Carboxylic Acids from Alkyl Halides with Three-Carbon Elongation
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概要
- 論文の詳細を見る
The reaction of the dianion of phenylsulfinylacetone with alkyl halides afforded β-keto sulfoxides, which were first chlorinated with hexachloroethane and then treated successively with KH and t-BuLi to give carboxylic acids in three-steps in moderate overall yields from the alkyl halides. This procedure affords a good method for a synthesis of carboxylic acids from alkyl halides with three-carbon elongation.
- 社団法人日本薬学会の論文
- 2003-05-01
著者
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今井 公江
Faculty Of Pharmaceutical Sciences Setsunan University
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Imai K
Univ. Tokyo Tokyo Jpn
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Satoh Tsuyoshi
Department Of Chemistry Faculty Of Science Tokyo University Of Science
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Satoh T
Department Of Chemistury Faculty Of Science Tokyo University Of Science
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Satoh Tsuyoshi
Department Of Agricultural Chemistry Obihiro University Of Agriculture And Veterinary Medicine
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IMAI Kentaro
Department of Chemistury, Faculty of Science, Tokyo University of Science
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Imai K
Department Of Chemistury Faculty Of Science Tokyo University Of Science
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Imai K
Department Of Bio-analytical Chemistry Graduate School Of Pharmaceutical Sciences The University Of
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