Antifatigue and Antistress Effect of the Hot-Water Fraction from Mycelia of Cordyceps sinensis
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概要
- 論文の詳細を見る
This study was conducted to investigate the chemical component of the hot water (HW) fraction of mycelia of Cordyceps sinensis and its antifatigue and antistress effect against a stimulus in vivo using rats and mice. The growth of mycelia reached a maximum level of 31.6 g/1 after 120 h of incubation. The main chemical composition of the HW fraction of mycelia of C. sinensis was found to be carbohydrate (78.9%) with 5% moisture. The swimming endurance capacity of mice orally administered with the HW fraction (150 and 300mg/kg/d, respectively) was significantly prolonged from 75 to 90 min with a lessening of fatigue. When the HW fraction (150 mg/kg/d) was given to rats for 8d including a 48 h stress period, the weight changes of the adrenal gland, spleen, thymus, and thyroid, which is an index of stress, were suppressed. The HW fraction also significantly inhibited the increase in total cholesterol and the decrease in alkaline phosphatase levels as biochemical parameters of immobilization stress in rats.
- 公益社団法人日本薬学会の論文
- 2003-05-01
著者
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Kim Jin-man
Department Of Pathology College Of Medicine Chungnam National University
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Kim Jin-man
Department Of Food And Nutrition College Of Health Sciences Korea University
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Kim Jin-man
Department Of Animal Science Kon-kuk University
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Kim Jin-man
Department Of Food And Biotechnology Yonsei University
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Kim Joong-man
Department Of Pharmacology College Of Oriental Medicine Kyung Hee University
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Suh Hyung-joo
Department Of Food And Nutrition College Of Health Sciences Korea University
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Song Jae-chul
Department Of Food And Nutrition University Of Ulsan
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Koh Jong-ho
Nel Biotech Research Institute Nel Biotech. Co. Ltd.
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KOH Jong-Ho
Obesity Research Center, Dongduk Women's University
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KIM Kyung-Mi
Obesity Research Center, Dongduk Women's University
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Kim Kyung-mi
Obesity Research Center Dongduk Women's University
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Koh Jonh-Ho
Obesity Research Center, Dongduk Women's University
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