Immunoreactive and Bioactive Atrial Natriuretic Peptide in the Carp Heart(Endocrinology)
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概要
- 論文の詳細を見る
Almost all of the secretory garnules in both the atrial and ventricular cardiocytes were immunolabeled. Chromatographic analysis of atrial and ventricular extracts indicated that the major component of immunoreactive ANP was a peptide with high molecular weight, which appeared to be equivalent to γ-ANP. These results suggest that ANP-like material is stored in the secretory granules in the atrial and ventricular cardiocytes of the carp, mainly as γ-type ANP. Furthermore, the atrial extracts showed a clear vasodepressor activity in quail, which disappeared after preincubation of the extract with excess antibodies raised against α-human ANP. Thus, immunoreactive and bioactive ANP in carp hearts may be identical.
- 社団法人日本動物学会の論文
- 1991-10-15
著者
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Nakamura S
Toyama Univ. Toyama Jpn
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Nakamura Sumio
Biological Laboratory Kanagawa Dental College
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Naruse Mitsuhide
Clinical Endocrinology Department Of Medicine Tokyo Women's Medical College
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UEMURA HARUKO
Biological Laboratory, Kanagawa Dental College
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TAKEI YOSHIO
Department of Physiology, Kitasato University School of Medicine
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HIROHAMA TOHRU
Biological Laboratory, Kanagawa Dental College
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ANDO KENJI
Kitasato Biochemical Laboratories
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AOTO TOMOJI
Biological Laboratory, Kanagawa Dental College
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Naruse Mitsuhide
Institute Of Clinical Endocrinology Department Of Medicine Tokyo Women's Medical University Sch
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Takei Yoshio
Department Of Physiology Ocean Research Institute The University Of Tokyo
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Ando Kenji
Kitasato Biocemical Laboratories.
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Aoto T
Biological Laboratory Kanagawa Dental College
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Uemura Haruko
Biological Laboratory Kanagawa Dental College
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Hirohama T
Kanagawa Dental Coll. Yokosuka Jpn
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Takei Yoshio
Department Of Physiology Kitasato University School Of Medicine
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Takei Yoshio
Department Of Pathology Division Of Neuropathology Emory University School Of Medicine
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