In Vivo and in Vitro Effects of a Protease Inhibitor (E-64) on Cell Division of Xenopus eggs : Biochemistry
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概要
- 論文の詳細を見る
Microinjection of E-64 into single blastomeres of Xenopus embryos at the 2-cell stage arrested cell division. In vitro treatment of cultured individual cells at the blastular embryonic stage with E-64 c also arrested the cleavages. We examined the effects of E-64 on the proteasome and calcium-activated protease in Xenopus embryos in vitro. E-64 inhibited calpain-like protease activity. Calpain-like protease activity was stimulated during cleavage. These results indicated that acalpain-like protease might be involved in the cell division of early Xenopus embryos.
- 社団法人日本動物学会の論文
- 2000-12-10
著者
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Ishii Takashi
Department Of Pharmacology Kanazawa Medical University
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AOKI Takehiko
Department of Dermatology, Yamagata University School of Medicine
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Miyata Shohei
Department of Chemistry, College of Humanities and Sciences, Nihon University
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Miyata S
Nihon Univ. Tokyo Jpn
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Miyata Shohei
Department Of Chemistry College Of Humanities And Sciences Nihon University
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Aoki Takehiko
School Of Medicine Juntendo University
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Hosoyama Yoshiyuki
Department of Chemistry, College of Humanities and Sciences, Nihon University
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Aoki Takehiko
Department Of Chemistry College Of Humanities And Sciences Nihon University
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Hosoyama Y
Nihon Univ. Tokyo Jpn
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Hosoyama Yoshiyuki
Department Of Chemistry Nihon University
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Ishii Takashi
Department Of Neurosurgery Bokuto Municipal Hospital Of Metropolitan Tokyo
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Ishii Takashi
Department Of Animal Science Faculty Of Agriculture Kyoto University
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Ishii Takashi
Department Of Chemistry College Of Humanities And Sciences Nihon University
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