積分器導入による Urethral Pressure Profile の定量化の試み

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The urethral pressure prfile was measured by the use of a two-eyed 14F Nelaton's catheter in 15 control adult males, 17 patients with benign prostatic hypertrophy and 15 patients with prostatism without prostatic enlargement. The catheter was passed at a speed of 30mm/min, using a flow rate of 1 to 2 ml/min. The parameters of UPP used in this study were the Max. P,FPUL and Area, as shown in Fig. 1. In the area measurement a multipurpose integrator was used, the application of which in this field has not been described to date. An α-adrenergic blocker was given in 10 of the 17 patients with benign prostatic hypertrophy and its effect was evaluated by the UPP. 1. There was no significant difference in Max. P between control adults and patients with benign prostatic hypertrophy and with prostatism. 2. There was no significant difference in FPUL between control adults and patients with prostatism, but the FPUL was significantly elongated in patients with benign prostatic hypertrophy. 3. The Area was progressively larger in the order of control adults, patients with prostatism and patients with prostatic hypertrophy, and the difference among the three groups was significant. 4. The α-adrenergic blocker elicited a decrease in the Area in all. In parallel with the change in UPP the residual urine decreased and the subjective symptoms improved. The results of this study suggest the usefulness of the α-adrenergic blocker as a conservative treatment of benign prostatic hypertrophy. 5. Calculation of the Area was considered to be useful in the evalution of UPP.
社団法人日本泌尿器科学会の論文

積分器導入による Urethral Pressure Profile の定量化の試み

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