腎腺癌の静脈内腫瘍栓塞と遠隔転移

概要

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Correlations among tumor emboli, distant metastasis, toxic clinical signs and prognosis of the patients in renal adenocarcinoma were investigated on 41 nephrectomized cases (II cases were alive over 5 years and 30 cases were dead) and on 25 autopsy cases. 1. Tumor emboli were recognized either by gross examination of the renal vein and its main branches and by microscopic detection of tumor emboli in small veins in 3-5 slides which were stained by elastica Van Giesen's stain. 2. There was a close correlation among tumor emboli, distant metastasis and prognosis. Cases in which embolus could not be recognized, distant metastasis was none or rare and the 5 year survival rate was high. In cases in whom tumor emboli were recognized, distant metastasis were often observed not only at the end stage but also at the relatively early stage, and the 5 year survival rate was low. 3. There was a close correlation between tumore mboli and clinical toxic signs, but in some cases there was no correlation. 4. Based on the close correlation among tumor emboli, clinical toxic signs and the prognosis of patients, we proposed a new system of classification of renal adenocarcinoma, which is as follows; Type 1 Cases with positive tumor emboli, and positive toxic signs. Type 2 Cases with positive tumor emboli, and negative toxic signs. Type 3 Cases with negative tumor emboli, and negative toxic signs.
社団法人日本泌尿器科学会の論文
1979-10-20