停留睾丸の内分泌学的研究 : 第3報 h.C.G.刺激による内分泌学的及び組織学的変化の検討

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This report describes the effect of human chorionic gonadtropin (HCG) on biosynthesis of testosterone, plasma testosterone concentration and histological findings of testes in cases with human unilateral cryptorchidism. The results are summarized as follows: 1. By administration of 4,000 IU of HCG for 3 days to cases with unilateral cryptorchidism it was noted that the conversion rate of progesterone to testosterone on undescended testes was proved to increase from 0.99±1.04% (N=12) to 9.13±3.88% (N=5) in 0-10 age group and from 7.9±2.20% (N=3) to 21.5±0.9% (N=2) in adult age group. 2. On the other hand, the conversion rate of contralateral testes increased from 3.73±3.78% (N=7) to 12.7±4.4% (N=4) in 0-10 age group, but decreased from 17.00±0.0% (N=1) to 5.77±0.0% (N=1) in 11-13 age group and from 19.3±0.0% (N=1) to 3.08±0.92% (N=2) in adult group. 3. Plasma testosterone concentration, including response following 3 days injections of 4,000 IU of HCG, was studied on 54 cases with cryptorchidism aged 1-35 years, and also examined on 30 healthy boys aged 1-17 years and 10 healthy girls aged 3-13 years as the controls. It was noted that under 10 years of age no difference of plasma testosterone concentration between cryptorchid boys (15.92±9.08 ng/dl) and normal boys (11.00±6.90 ng/dl). A significantly higher testosterone response (214.4±123.4 ng/dl) to HCG was demonstrated in prepubertal cryptorchid patients.
社団法人日本泌尿器科学会の論文
1976-10-20

停留睾丸の内分泌学的研究 : 第3報 h.C.G.刺激による内分泌学的及び組織学的変化の検討

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