上部尿路機能に関する研究 : 第8報急速利尿時における犬生体腎盂尿管の動態

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The present investigation was undertaken in order to clarify the mechanism of the transport of urine by the pelvi-ureteral system in dogs. Twenty-eight preparations of exteriorized renal pelvis and ureter from 18 dogs were used. Dogs were operated under thiopental anesthesia. The pelvis and ureter were exposed transperitoneally, and electrodes were implanted at the pelvis and ureter. Simultaneous recordings of pelvic and ureteral myograms were obtained. A vein needle connected to a pressure transducer was placed in the pelvis and pressure within the pelvis was recorded. For measurement of intraureteral pressure, a No.18 gauge scalp vein needle was inserted into the ureter below the site of implanted electrode. These measurements were made simultaneously with myogram recordings. The changes in pelvic and ureteral peristalsis were recorded, together with the corresponding myogram and pressure recordings after rapid diuresis induced by an intravenous infusion of Furosemide (10-20mg). Results: 1) The average frequency of contraction before induced diuresis was 24.6 times per min. in the pelvis and 8.7 times per min. in the ureter. Namely, the peristaltic frequency of the pelvis before diuresis was greater than that of the ureter by a ratio of 3:1. 2) During diuresis, the average frequency of contraction was 24.1 times per min. in the pelvis and 22.7 times per min. in the ureter, indicating that the peristaltic activity of the ureter increased as the urine volume increased.
社団法人日本泌尿器科学会の論文

上部尿路機能に関する研究 : 第8報急速利尿時における犬生体腎盂尿管の動態

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