老人性膀胱頸部硬化症の組織学的研究

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A histological examination was carried out on the bladder neck sclerosis of the aged. Specimens were obtained at the operation (perineal or retropublic prostatectomy with bladder neck reconstruction). Besides hematoyxlin-eosin (HE) staining, alcian blue-periodic acid Schiff (AB-PAS) staining, toluidine blue (TB) staining, van Gieson (v.G.) staining and Weigert staining were performed. The proliferation of collagen fibers, which is presumed to be a senile change, appeared to be the essential histological finding of the bladder neck sclerosis. The proliferated collagen fibers can be observed clearly by v.G. staining even on the tissues where they are not detected by HE staining. Since the infiltration of chronic inflammatory cells is often accompanied by the proliferation of collagen fibers, it is suspected that chronic infection can induce and accelerate the sclerotic changes of the bladder neck.
社団法人日本泌尿器科学会の論文
1976-07-20

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