ビタミンB_2より誘導されるキノキザリン化合物に関する栄養的意義

概要

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Riboflavin content in urine of a rabbit to which 6,7-dimethyl-2-keto-1-D-ribityl-3-quinoxaline carboxylic acid (B_2-keto acid) was given subcutaneously reached its highest level in 4-6 hours after the injection. There was also an obvious increaa of riboflavin in urine in a day. Riboflavin content in urine increased even when sulfamine and B_2-keto acid were given at the same time, but the content was less than when sulfamine was not given. The riboflavin content in liver and kidney of a mouse increaed in 2-4 hours after B_2-keto acid had been given. In this case, the given B_2-keto acid was not detected in organs by the paper partition chromatography. From these results it was concluded that B_2-keto acid activated the riboflavin metabolism and increased the riboflavin content in urine.
日本ビタミン学会の論文