微生物の生産する抗菌性物質(第9報) : Ferromycin生産に於ける深部培養について

概要

論文の詳細を見る
The relation between the oxygen absorption rate and ferromcin yield in 30l and 180l tanks was examined.The effect of aeration rate on the ferromycin production was very small in the 30l fermentor and pilot tank, but agitator speed has a great influence on it. So the accurate correlation between oxgen absorption coefficient and ferromycin production could not be recognized. In the 30l fermentor, 300 r.p.m. was the optimum speed for feeromycin production, whereas in the 180l fermentor, 250 r.p.m. gave best results. As regards seration rate, no significant difference in ferromycin production was observed in the range of 0.5 vvm to 2 vvm.The peak of O_2 uptake may be an indicator of ferromycin fermentation yield, but no significant change in the minimum value of dissolved oxygen in the broth was observed under the conditions tested.We calculated the oxygen absorption rate throughout the culture period by the following formula.(O.A.R.)'=Io_2・Po_2/63(C^*-C_L)This value was presumed to be applicable as a parameter for ferromycin fermentation yields.
社団法人日本生物工学会の論文
1961-01-15