Practical Production of(S)-1, 2-Propanediol and Its Derivative through Baker's Yeast-Mediated Reduction
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概要
- 論文の詳細を見る
The enantiomeric excess(ee)of(S)-1, 2-propanediol produced by baker's yeast-mediated reduction of 1-acetoxy-2-propanone was improved to 96% ee by a fed-batch operation of the substrate. A similar reduction of 1-benzoyloxy-2-propanone stopped because of the inhibition toward the enzymes for NADPH regeneration by the reduction product. The inhibition was prevented using resin that adsorbs the product from the reaction mixture, and 70 g/l substrate was reduced yielding(S)-1-benzoyloxy-2-propanol at >99% ee.
- 社団法人日本生物工学会の論文
- 2001-05-25
著者
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GOTO Michimasa
Department of Chemical and Biochemical Engineering
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KOMETANI Tadashi
Department of Chemical and Biochemical Engineering
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Goto M
Department Of Chemical And Biochemical Engineering Toyama National College Of Technology
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Kometani Tadashi
Department Of Biochemical Engineering Toyama National College Of Technology
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TOIDE HISAE
Department of Chemical and Biochemical Engineering, Toyama National College of Technology
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DAIKAIJI YUKO
Department of Chemical and Biochemical Engineering, Toyama National College of Technology
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Toide Hisae
Department Of Chemical And Biochemical Engineering Toyama National College Of Technology
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Daikaiji Yuko
Department Of Chemical And Biochemical Engineering Toyama National College Of Technology
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