Cutinostatin B as a New Cutinase Inhibitor Produced by Actinomycete
スポンサーリンク
概要
- 論文の詳細を見る
Cutinostatin B was purified from a culture filtrate of a strain No.3112-4 of an actinomycete which had been isolated from a soil sample collected in Setagaya-ku, Tokyo, Japan. The structure of this compound was determined mainly by 2D NMR experiments to be N^α-[N^α-(2,3-dihydroxybenzoyl)-ornithyl]-N^δ-hydroxyornithine-δ-lactum. Cutinostatin B inhibited the cutinase activity of Cladosporium fulvum when using β-naphthyl caproate as the substrate with an IC_<50> value of 28.9μM (11.0μg/ml), and inhibited 95% when using crude apple cutin as the substrate with a concentration of 263μM (100μg/ml).
- 社団法人日本農芸化学会の論文
- 1996-03-23
著者
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HIGASHI Kazuaki
Department of Applied Biological Chemistry, Tamagawa University
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Hori Hiroshi
Department Of Applied Biological Chemistry Tamagawa University
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Hirose Jun
Department Of Applied Chemistry Miyazaki University
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Higuchi Hiroko
Biotechnology Research Center Toyama Prefectural University
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Ishiyama Tadayuki
Department Of Applied Biological Chemistry Tamagawa University
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Higashi K
Department Of Applied Biological Chemistry Tamagawa University
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Hirose Jun
Department Of Agricultural Chemistry Faculty Of Agriculture Tamagawa University
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ISHIYAMA Tadayuki
Department of Agricultural Chemistry, Faculty of Agriculture, Tamagawa University
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