Aspergillomarasmine A and B, Potent Microbial Inhibitors of Endothelin-converting Enzyme
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概要
- 論文の詳細を見る
When screening for inhibitors of endothelin-converting enzyme (ECE), we isolated and identified Aspergillomarasmine A and B (AM-A and B) as potent inhibitors of ECE from the cultute broth of Paecilomyces sp. N877. Both AM-A and AM-B had apparent activity in an in vivo experiment with big ET-1 induced sudden death, although the inhibitory activities of these compounds would be mainly due to the chelating effect.
- 社団法人日本農芸化学会の論文
- 1993-11-23
著者
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Matsuura A
Amano Pharmaceutical Co. Ltd. Aichi Jpn
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Matsuura Akihiro
Oral Surgery Sapporo Medical University School Of Medicine
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Matsuura Akihiro
Department Of Applied Chemistry Nagoya Institute Of Technology
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Matsuura Akihiro
Shimizu Research Laboratories Reseach And Development Division Shimizu Pharmaceutical Co. Ltd.
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Munekata Masanobu
Pharmaceutical Research Laboratories Sapporo Breweries Ltd.
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ARAI Koshi
Pharmaceutical Research Laboratories, Sapporo Breweries Ltd.
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Ashikawa Nami
Pharmaceutical Research Laboratories, Sapporo Breweries Ltd.
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Nakakita Yasukazu
Pharmaceutical Research Laboratories, Sapporo Breweries Ltd.
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Matsuura Akihiro
Pharmaceutical Research Laboratories, Sapporo Breweries Ltd.
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Ashizawa Naoki
Pharmaceutical Research Laboratories, Sapporo Breweries Ltd.
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Arai K
Tokyo Noko Univ. Tokyo Jpn
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Arai Koshi
Pharmaceutical Research Laboratories Sapporo Breweries Ltd.
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Ashizawa N
Grelan Pharmaceutical Co. Ltd. Tokyo Jpn
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Ashizawa Naoki
Pharmaceutical Research Laboratories Research Center Research And Development Division Grelan Pharma
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Miyazaki Akihiro
Oral Surgery Sapporo Medical University School Of Medicine
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Nakakita Yasukazu
Brewing Research Laboratories Sapporo Breweries Ltd.
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Matsuura Akihiro
Pharmaceutical Research Laboratories Research Center Research And Development Division Grelan Pharma
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