Microbial Glycosylation and Acetylation of Brefeldin A
スポンサーリンク
概要
- 論文の詳細を見る
The brefeldin A (BFA) derivatives 4-O-acetyl BFA, 7-O-acetyl BFA, and 4-O-D-glucosyl BFA were found by the microbial conversion of BFA. 4-O-D-Glucosyl BFA is a novel compound produced by the conversion of BFA with Streptomyces sp. Q53834. The cytotoxicity and antifungal activity of all of the compounds were markedly less than those of BFA.
- 社団法人日本生物工学会の論文
- 2003-10-25
著者
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Suzuki K
Astellas Research Service Co. Ltd. Astellas Pharma Inc.
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YAMAMOTO TOMOKO
Department of Microbiology and Molecular Genetics, Graduate School of Pharmaceutical Sciences, Chiba
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SUZUKI KENICHI
Microbiology Laboratories, Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd
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SHIBAZAKI TSUYOSHI
Microbiology Laboratories, Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd
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YAMAGUCHI HIROSHI
Microbiology Laboratories, Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd
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SUGAWARA TAKEO
Project Coordination Department, Drug Development Division, Yamanouchi Pharmaceutical Co., Ltd.
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Sugawara Takeo
Project Coordination Department Drug Development Division Yamanouchi Pharmaceutical Co. Ltd.
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Yamamoto Tomoko
Department Of Biochemistry Faculty Of Pharmaceutical Sciences The University Of Tokushima
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Suzuki Kenichi
Microbiology Laboratories Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. Ltd.
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Suzuki Ken-ichi
Astellas Research Service Co. Ltd. Astellas Pharma Inc.
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Shibazaki Tsuyoshi
Microbiology Laboratories Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. Ltd.
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Shibazaki Mitsuyoshi
Microbiology Laboratories Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. Ltd.
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Yamaguchi H
Department Of Applied Biology Faculty Of Textile Science And Technology Shinshu University
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Yamamoto Tomoko
Department Of Applied Chemistry Keio University
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Yamamoto Hiroaki
Department Of Developmental Biology And Neurosciences Graduate School Of Life Sciences Tohoku Univer
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Yamamoto Hiroaki
Department Of Developmental Biology And Neurosciences Graduate School Of Life Sciences Tohoku Univer
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Suzuki Kenichi
Microbiology Laboratories Institute For Drog Discovery Research Yamanouchi Pharmaceutical Co. Ltd
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