HISTOCHEMICAL STUDY ON 5'-NUCLEOTIDASE IN THE CEREBROVASCULAR SYSTEM IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS
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概要
- 論文の詳細を見る
5'-Nucleotidase activity in the cerebrovascular system in stroke-prone spontaneously hypertensive rats was histochemically investigated. In the hypertensive rats, an enhancement of 5'-nucleotidase activity was observed already in the early stage of hypertension and the anzyme activity increased with advancing age. The enzyme activity appeared earlier and stronger in the larger arteries in the basal portion than the pial arteries in the convexity of the brain and arterioles in the brain parenchyma. The activity in the arterial walls proved to be particularly strong in the thickened parts showing cellular hyperplasia, mainly at the branching portions. The reaction products localized along the plasma membrane, and also in the cytoplasma in some parts where the activity was strong. Relationship between the increased 5'-nucleotidase activity and aging of the cells composing the cerebrovasculature resulted from an accelerated or repeated cell proliferation was discussed.
- 社団法人日本循環器学会の論文
- 1981-11-20
著者
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MATSUMOTO MASAO
Department of Palhology, Faculty of Medicine, Kyoto University
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HAZAMA Fumitada
Department of Pathology, Faculty of Medicine, Kyoto University
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Matsumoto Masao
Department Of Palhology Faculty Of Medicine Kyoto University
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YAMADA Eiji
Department of Pathology, Shiga University of Medical Science
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AMANO Shigeru
Department of Pathology Shiga University of Medical Science
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Yamada Eiji
Department Of Pathology Shiga University Of Medical Science School Of Medicine
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Amano Shigeru
Department Of Pathology Shiga University Of Medical Science School Of Medicine
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Hazama Fumitada
Department Of Pathology Kyoto University Faculty Of Medicine:max-planck Institut Fur Psychiatrie:(pr
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OHKAWA KENICHI
Department of Cytochemistry, Chest Disease Research institute, Kyoto University
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Ohkawa Kenichi
Department Of Cytochemistry Chest Disease Research Institute Kyoto University
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Amano Shigeru
Department Of Oral Biology And Tissue Engineering Meikai University School Of Dentistry
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Yamada Eiji
Department Of Civil Engineering Nagoya University
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Matsumoto Masao
Department Of Pathology Shiga University Of Medical Science School Of Medicine
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Yamada Eiji
Department Of Child Development Kumamoto University School Of Medicine
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Matsumoto Masao
Department Of Medical Engineering Osaka University Graduate School Of Medicine
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Amano Shigeru
Department of neurosurgery, Kyoto University Medical School
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Hazama Fumitada
Deparment of Pathology, Shiga University of Medical Science, School of Medicine
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Amano Shigeru
Department of Laboratory Science, Kyoto University Graduate School of Medicine, Japan
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