CYTOCHEMICAL INVESTIGATION ON ACID PHOSPHATASE ACTIVITY IN CEREBRAL ARTERIES IN SPONTANEOUSLY HYPERTENSIVE RATS
スポンサーリンク
概要
- 論文の詳細を見る
Acid phosphatase activity in the cerebral arterial system in spontaneously hypertensive rats (SHR) was cytochemically investigated. In the endothelial and medial smooth muscle cells, endoplasmic reticulums and Golgi complex revealed an intense acid phosphatase activity and primary lysosomes containing the high enzyme activity were found to be augmented in number. The enzyme activity was demonstrated in the vacuolated secondary lysosomes and in the intercellular spaces of the arterial walls. Lytic changes of the arterial mural cells and vessel matrix due to lysosomal enzymes were also evident. Causes of the lysosomal enzyme induction and roles of the enzyme in the developmental mechanism of hypertensive cerebrovascular changes in the SHR brain are discussed.
- 社団法人日本循環器学会の論文
- 1980-07-20
著者
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HAZAMA Fumitada
Department of Pathology, Faculty of Medicine, Kyoto University
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HANAKITA Junya
Department of Neurosurgery and Department of Pathology, Shizuoka General Hospital
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YAMADA Eiji
Department of Pathology, Shiga University of Medical Science
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AMANO Shigeru
Department of Pathology Shiga University of Medical Science
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Yamada Eiji
Department Of Pathology Shiga University Of Medical Science School Of Medicine
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Amano Shigeru
Department Of Pathology Shiga University Of Medical Science School Of Medicine
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Hanakita Junya
Department Of Neurosurgery Faculty Of Medicine Kyoto University
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Hanakita Junya
Department Of Neurosurgery And Department Of Pathology Shizuoka General Hospital
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Hazama Fumitada
Department Of Pathology Kyoto University Faculty Of Medicine:max-planck Institut Fur Psychiatrie:(pr
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Amano Shigeru
Department Of Oral Biology And Tissue Engineering Meikai University School Of Dentistry
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Yamada Eiji
Department Of Civil Engineering Nagoya University
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Yamada Eiji
Department Of Child Development Kumamoto University School Of Medicine
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Hazama Fumitada
Deparment of Pathology, Shiga University of Medical Science, School of Medicine
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Amano Shigeru
Department of Laboratory Science, Kyoto University Graduate School of Medicine, Japan
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