Macroscopic Hemorrhagic Infarction Following Selective Coronary Thrombolysis In Acute Myocardial Infarction : PANEL DISCUSSION ONINTRACORONARY THROMBOLYSIS BY THROMBOLYTIC AGENTS AND PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY
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概要
- 論文の詳細を見る
Macroscopic hemorrhagic infarction was studied in 14 autopsied hearts with selective coronary thrombolysis (SCT) after acute myocardial infarction (AMI). In all patients urokinase, 240,000-720,000 units, had been selectively injected into ischemia-related coronary artery at 2-7 hours after the onset of AMI. The degree of stenosis after SCT was 90-99% in 13 patients and 100% in one patient. According to the duration of illness at death, the 14 patients were classified into 3 stages; stage I: 4-9 hours; stage II: 15 hours to 11 days; stage III: 19 days to 12 months. Three hearts in stage I had no macroscopic hemorrhage. In stage II, marked and diffuse hemorrhage in the infarct area was macroscopically evident in 6 of 7 hearts. In a stage II patient, extravasation of contrast medium into the myocardium was found at 3 hours after the onset of AMI. In stage III, 4 hearts had massive fibrosis or granulation in the left ventricular wall without macroscopic hemorrhage. Cardiac rupture was seen in 4 of 10 patients from stages I and II. It is concluded that macroscopic bleeding appears in most patients with AMI treated with coronary thrombolysis. In the majority of cases, the hemorrhage increases gradually after SCT and becomes macroscopically definite approximately 15 hours after the onset of AMI. Rarely, massive bleeding appears earlier. Hemorrhagic infarction is replaced by massive fibrosis after approximately 2 weeks.
- 社団法人日本循環器学会の論文
- 1985-06-20
著者
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Fujiwara Takako
Kyoto Women's University
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Takahashi Masaaki
The Third Division Department Of Internal Medicine Kyoto University
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Wu Der-jinn
Chung Shang Medical University Hospital
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Hamashima Yoshihiro
Department Of Biomaterials Institute For Frontier Medical Sciences Kyoto University
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FUJIWARA HISAYOSHI
The Third Division,Department of Internal Medicine, Faculty of Medicine, Kyoto University
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Tanaka Masahiro
Rakuwakai Otowa Hospital
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Yokoyama Haruko
Department Of Biomaterials Institute For Frontier Medical Sciences Kyoto University
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Kawai Chuichi
The Third Division Department Of Internal Medicine. Faculty Of Medicine Kyoto University
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Onodera Tomoya
Department Of Cardiovascular Surgery And The Third Division Department Of Internal Medicine Kyoto Un
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Fujiwara Takako
Kyoto Women's University
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Tanaka Masaru
The Third Division of Medicine, Kyoto University
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WU DER-JINN
The Third Division, Department of Internal Medicine ,Kyoto University
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ONODERA TOMOYA
The Third Division, Department of Internal Medicine ,Kyoto University
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Fujiwara Hisayoshi
The Third Division Of Internal Medicine Kyoto University
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Kawai Chuichi
The Third Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Kawai Chuichi
3rd Div. Dept Of Intern Med. Kyoto Univ
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Wu Der-jinn
The Third Division Departments Of Internal Medicine
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Hayakawa Yukihiro
Department Of Biomaterials Institute For Frontier Medical Sciences Kyoto University
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Yokoyama Haruko
Regeneration & Advanced Medical Science
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Tanaka Masaru
Department Of Cardiology Cardiovascular Center Osaka Red Cross Hospital
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Kawai Chuichi
Department Of Internal Medicine 3rd Division Faculty Of Medicine Kyoto University
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Tanaka Masaru
The Third Division Of Medicine Kyoto University
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Tanaka Makoto
Cardiovascular Center Osaka Red Cross Hospital
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Fujiwara Hisayoshi
The Third Division Department Of Internal Medicine Faculty Of Medicine Kyoto University Kyoto
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Onodera Tomoya
Department Of Cardiovascular Surgery And The Third Division Department Of Internal Medicine Kyoto Un
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