DIFFERENCE IN MYOCARDIAL CHARACTERISTICS BETWEEN HYPERTROPHIC CARDIOMYOPATHY AND MYOCARDIAL HYPERTROPHY DUE TOESSENTIAL HYPERTENSION

概要

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To investigate the qualitative difference in myocardial hypertrophy that exists between hypertrophic cardiomyopathy (HCM) and essential hypertension (HT), we measured the mean wall thickness (MWT), the early diastolic time intervals (II_A-MVO time: from the second heart sound to the point of mitral valve opening, MVO-O time: from MVO to the O point of apexcardiogram) and the MVO-O/II_A-MVO ratio. The MWT in HCM and HT was measured by biventriculogram and echocardiogram, respectively. The MWT showed no significant difference between HT (1.31±3.0 mm) and non-obstructive type of HCM (14.8±3.7), but the MWT in obstructive type (1.08±0.24) was significantly thinner than that in HT. As the MWT increased, both II_A-MVO and MVO-O time were prolonged in both groups. But the mode of prolongation was quite different. In HT, the prolongation of the II_A-MVO time was almost always greater than that of MVO-O time. In HCM, the prolongation of the latter was greater than that of the former. The MVO-O/II_A-MVO ratio in HT was significantly greater. These findings suggest that the differences in the early diastolic time intervals between HCM and HT are not due to the magnitude of the left ventricular hypertrophy, but due to myocardial characteristics.
社団法人日本循環器学会の論文
1985-03-20