DIAGNOSTIC SIGNIFICANCE OF EARLY DIASTOLIC TIME INTERVALS IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY AND MYOCARDIAL HYPERTROPHY DUE TO ESSENTIAL HYPERTENSION

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In order to differentiate hypertrophic cardiomyopathy (HCM) from myocardial hypertrophy due to essential hypertension (HT), echocardiogram, apexcardiogram and phonocardiogram were simultaneously recorded in patients with HCM (n =22), HT (n = 34) and normal subjects (N) (n=22). The following early diastolic time intervals were measured : 1) II_A-O time, 2) II_A-MVO time (IRT) and 3) MVO-O time. The II_A-O time was 119 ± 9 msec in N, 159 ± 31 in HT (p < 0.001, vs N) and 228 ± 57 in HCM (p < 0.001, vs N and HT, respectively). The II_A-MVO time was 66 ± 11 msec in N, 95 ± 18 in HT (p < 0.001, vs N) and 102 ± 24 in HCM and 126 ± 48 in HCM (p < 0.001, vs N and HT, respectively). These results showed that among the early diastolic time intervals HT was abnormal only in the II_A-MVO time. On the other hand, HCM had abnormalities not only in the II_A-MVO time but also in the MVO-O time. Both the II_A-MVO and the MVO-O times in hypertrophic non-obstructive cardiomyopathy were prolonged significantly as compared to those in obstructive one. Analysis of early diastolic time intervals may be very useful to differentiate HCM, especially of the non-obstructive type, from HT.
社団法人日本循環器学会の論文
1983-05-20