ヘパリン加シリンジの血液ガス・電解質測定に及ぼす影響

概要

論文の詳細を見る
In order to test the hypothesis whether the amount of heparin in commercially available heparinized syringes affects the results of blood gas and electrolyte analysis, syringes with 15 and 45 units of heparin (#4528,and PDX-296,Concord Laboratory, Inc., U.S.A, respectively) were evaluated. 129 pairs of blood samples were measured, while 0.5 ml of whole blood was collected in both syringes. The concentrations of sodium and ionized calcium were significantly greater in the syringe with 15 units of heparin than those in the syringe with 45 units. Such significant difference in concentrations of ionized calcium and sodium between the two syringes was probably secondary to the dose-dependent chelation of cations by heparin. The difference in ionized calcium was 8.2%, and it is considered as clinically significant. The present study suggests that the heparinized syringe should contain the minimum amount of heparin for the accurate measurement of electrolyte.
日本医療機器学会の論文
1990-05-01