726 細胞の力学特性検知システムの開発

概要

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In this study , a method of sensing is specifically developed to detect dynamic characteristics in living cells. Experimental studies have been carried out by using the killifish's egg cell. Micro wire plastic needle was bonded on the tip of the sensor vibrator so as to detect dynamic characteristics of the cells. The sensor was controlled by micromanipulator system, while dimensions and morphologies of the cells were measured by inverted phase-contract microscope system connected to a CCD video camera. It is found that frequency characteristics obtained from the experiments reflected material properties of the cells. Also the sensor can detect changes of material properties of the cells due to fertilization. Thus, the present method has enough possibilities to detect dynamic characteristics of cells and cellular tissue.
一般社団法人日本機械学会の論文
2000-09-01