7.小児期リウマチ熱及び重症筋無力症に於ける血清補体価について(第3回補体シンポジウム II 各種疾患における補体及び補体成分の変動)

概要

論文の詳細を見る
There are some reports that immunological mechanism has a significant role in the occurence of rheumatic carditis and myasthenia gravis. We estimated a serum complement levels of chidren with rheumatic fever and myasthenia gravis by Mayer's method. Of 17 patients with rehumatic fever, 7 cases are with carditis and 10 without carditis. In acute phase, the mean value of serum complement was 35.3 C.H 50/ml in cases with carditis and 26.6 in cases without carditis. And in remission the mean values were 29.8 and 33.4 respectively. These results sugest that an immunological mechanism has some relationship to the occurrence of rheumatic carditis. Conserning myasthenia gravis, serum complement levels of 25 patients were estimated. Five of them were general type and 20 were occular type. The mean complement level was 21.9 in general type and 26.2 in occural type. In remissive phases, though we had only 3 cases, mean value was 30.0, respectively. We had 2 cases of occular type with a waining phenomenon in E.M.G., and their serum complement levels were rather lower. The waining phenomenon indicates that general muscles are involved, so we can regard such a case as a general type. These two types of myasthenia gravis can be said to be different from each other in the stand point of complementology.
日本アレルギー学会の論文
1966-11-30