IgD 抗核抗体について

概要

論文の詳細を見る
IgD is one of the immunoglobulins discovered by Rowe and Fahey in 1965. Much remains to be known about the nature and function of IgD. IgD antibody, in particular, the antinuclear factor (ANF) was investigated in 42 cases of systemic lupus erythematosus (SLE) and possible SLE with positive ANF. IgD ANF was demonstrated in 6 out of 42 cases (14%) by means of fluorescent antibody 4-layer method, however, the antibody titers were low in all cases. The complement fixation test was negative. All cases with positive IgD ANF were below the age 29 and their illness was within one year after the onset. Their titers of IgG ANF were all exceeding 64. In contrast to cases with negative IgD ANF, no significant correlation was found between severity of the disease, LE cell phenomenon and the degree of proteinuria.
一般社団法人日本アレルギー学会の論文
1969-10-30