銅とポリカプロラクトンとの複合材料の酵素リパーゼによる生分解特性に及ぼすMA時間の影響

概要

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To evaluate the biodegradability of polycaprolactone (PCL) 50 vol%Cu composites produced by the mechanical alloying (MA) method, degradation tests by lipase have been performed for some mechanical alloying time of the composites. As the results, total oxygen content and the weight decreasing rate caused by biodegradation have lower values at the long-time mechanical alloyed composites, while at the short-time mechanical alloyed composites have that of higher value. This results indicate that the biodegradability of the composites decrease with increasing the MA time. The cause of these results can be explained that the composites are not perfectly degraded, because it decomposes from the circumference of the metal powders aggregates at the short-time mechanical alloyed composites. On the other hand, the lower biodegradability in the long-time mechanical alloyed composites is probably caused by uniformity dispersion of copper powder in the PCL, because biodegradation occur successively from the outer layer.
一般社団法人日本機械学会の論文
2001-04-25