リン酸水素カルシウムとリン酸水素ナトリウム水溶液による水酸化カルシウム製剤への自己硬化性付与

概要

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Although a calcium hydroxide preparation is widely used in dental clinics as a base liner and a root canal filling material, its very high basicity causes necrosis of the dental pulp and it does not set. In this study, we evaluated the feasibility of developing a calcium hydroxide preparation that has a good setting ability and a moderate basicity. The calcium hydroxide preparation examined showed a good setting ability and formed an apatitic mineral upon setting when dicalcium phosphate anhydrous (DCPA) powder was added and mixed with sodium hydrogen phosphate aqueous solution. Setting mechanism had a close relationship with apatite formation. As a result of the addition of DCPA, that is, acidic calcium phosphate, the calcium hydroxide preparation showed a relatively mild basicity when compared with the DCPA-free calcium hydroxide preparation. An animal study demonstrated that a calcium hydroxide preparation containing DCPA causes less inflammatory response at the initial stage and elicits faster secondary dentin formation than DCPA-free calcium hydroxide preparation. We concluded therefore that a calcium hydroxide preparation containing DCPA is a promising alternative to the calcium hydroxide preparation currently used in dental clinics.
社団法人日本セラミックス協会の論文
2004-08-01