Endocrine Functions in Children with Suprasellar Germinoma
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概要
- 論文の詳細を見る
Clinical manifestations and endocrine functions were evaluated in 17 children with suprasellar germinoma. Polyuria and growth retardation were the most common initial symptoms. Physical and neurological examinations revealed diabetes insipidus in 17, growth retardation in five, and visual disturbance in three of the patients. Assessment of hypothalamic-pituitary function before treatment revealed pituitary deficits in all patients involving growth hormone, thyroid-stimulating hormone, luteinizing hormone, follicle-stimulating hormone, and adrenocorticotropic hormone. These pituitary dysfunctions persisted after tumor remission due to radiation therapy. These results indicate that children with suprasellar germinoma need long-term hormone replacement therapy to prevent growth retardation, thyroid dysfunction, and delayed secondary sexual development.
- 日本脳神経外科学会の論文
- 1993-03-15
著者
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Abe Hiroshi
Department Of Cardiology National Cardiovascular Center
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Fujieda Kenji
Department of Pediatrics, Asahikawa Medical College
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MATSUURA NOBUO
Department of Pediatrics, Kitasato University School of Medicine
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Fujieda Kenji
Department Of Pediatrics Asahikawa Medical College
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Fujieda Kenji
Department Of Pediatrics Hokkaido University School Of Medicine
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Matsuura Nobuo
Department Of Child Studies Seitoku University Faculty Of Humanities
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Matsuura Nobuo
Department Of Pediatrics Hokkaido University School Of Medicine
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AIDA Toshimitsu
Department of Neurosurgery, Hokkaido University School of Medicine
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Abe Hiroshi
Department Of Neurosurgery Hokkaido University School Of Medicine
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Abe Hiroshi
Department Of Anatomy Akita University School Of Medicine
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Aida Toshimitsu
Department Of Neurosurgery Hokkaido University School Of Medicine
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Aida Toshimitsu
Department Of Neurosurgery Hokkaido University School Of Medicine:m.d. Department Of Neurosurgery Ha
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Abe Hiroshi
Department Of Agricultural Chemistry Faculty Of Agriculture Tohoku University
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MATSUURA Nobuo
Department of Pediatrics, Hokkaido University School of Medicine
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