Neurotoxicity Testing of a New Bioactive Bone Cement

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概要

• 論文の詳細を見る

• Bioactive bone cement (BABC) is a novel artificial bone cement. It has some noteworthy characteristics that are applicable to neurological surgery. The toxicity of BABC to the nervous system was tested by implanting BABC and polymethylmethacrylate (PMMA) cement as a control at the parietal and the suboccipital regions of the skull in beagles. The auditory brainstem response (ABR) was tested before and after implantation. Sections of the cerebral cortex and the acoustic nerve were examined at 3 and 6 months after implantation. No abnormal ABR was found in any animals. Histological examination of the cerebral cortex and acoustic nerve demonstrated slight gliosis in both the BABC and PMMA cement groups, but no other abnormalities.

• 日本脳神経外科学会の論文
• 1997-02-15

著者

• ISHIKAWA Masatsune

  Department of Neurosurgery, Tazuke-Kofukai Kitano Hospital

• Nakamura Takashi

  Department of Cardiology, Saiseikai Shigaken Hospital

• Nagata Izumi

  Department Of Neurosurgery Faculty Of Medicine Kyoto University

• Kikuchi Haruhiko

  Department Of Neurosurgery National Cardiovascular Center

• Kikuchi Haruhiko

  Department Of Agricultural Chemistry The University Of Tokyo

• Takahashi Jun

  Department Of Cardiology Iwate Prefectural Central Hospital

• Oda Yoshifumi

  Department Of Neurosurgery Kobe City General Hospital

• Oda Yoshifumi

  Departments Of Neurosurgery Faculty Of Medicine Kyoto University

• Takahashi Jun

  Departments Of Neurosurgery Faculty Of Medicine Kyoto University

• Kikuchi Haruhiko

  Department Of Neurosurgery Facuulty Of Medicine Kyoto University

• MURAI Nozomu

  Departments of Neurosurgery, Faculty of Medicine, Kyoto University

• Ishikawa Masatsune

  Departments Of Neurosurgery Faculty Of Medicine Kyoto University

• Ishikawa Masatsune

  Department Of Neurosurgery Faculty Of Medicine Kyoto University

• Ishikawa Masatsune

  Department Of Neurosurgery And Pharmacology Faculty Of Medicine Kyoto University

• Murai Nozomu

  Departments Of Neurosurgery Faculty Of Medicine Kyoto University

• Nagata Izumi

  Departments Of Neurosurgery Faculty Of Medicine Kyoto University

• Nakamura Takashi

  Department Of Cardiology Saiseikai Shiga Hospital

• Nagata Izumi

  Department Of Neurosurgery Facuulty Of Medicine Kyoto University

• Kikuchi Haruhiko

  Department Of Neurosurgery Iwate Medical University

• TAKAHASHI Jun

  Department of Applied Chemistry and Biotechnology, University of Fukui

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