Primitive neuroectodermal tumor (PNET)と診断された巨大子宮腫瘍の1例

概要

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Primitive neuroectodermal tumors (PNET) of the uterus are rare and aggressive tumors which are associated with high morbidity and mortality. A 48-year-old woman who presented with an enlarged uterus was diagnosed as PNET of the uterus. Tumor markers such as CA19-9, CAl25, CEA and ALP were within normal limits, but the serum LDH level was abnormally high. The patient underwent abdominal total hysterectomy with bilateral salpingooophorectomy. The microscopic examination showed a dense cell tumor of small neuroendocrine cells with rosettes. Immunohistochemically, the cells were positive for NSE and CD99 (MICE2), and negative forS-100, Keratin and Desmin. The patient was treated with CBDCA and Etoposide. She is with no evidence of recurrent disease eight months after the surgery.
社団法人日本産科婦人科学会の論文
2000-01-01