抗甲状腺抗体陽性妊婦における産後の甲状腺機能

概要

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The aim of this study was to elucidate a risk for thyroid dysfunction after delivery in women who had norman thyroid function and positive test for anti-thyroid antibodies during pregnancy. Between April 1994 and March 1997, we examined thyroid tests in 1,674 pregnant women. The thyroid tests included thyroid stimulating hormone, free thyroxine, anti-microsome antibody, and antithyroglobulin antibody. Excluding 61 women with a history of thyroid disease or abnormal thyroid function, the incidences of post-partum abnormal thyroid function were 6.3% at 1 month and 19% at 3 months in women with a positive test for anti-thyroid antibodies, whereas they were 6.7% and 4.9%, respectively, in women with a negative test for anti-thyroid antibodies. The incidence of abnormal thyroid function at 3 months after delivery was significantly high in women with anti-thyroid antibodies. This finding suggests the need for post-partum management and follow-up for thyroid function, especially in women with anti-thyroid antibodies.
社団法人日本産科婦人科学会の論文
1999-07-01