腹膜原発の表在性漿液性乳頭状腺癌の臨床的検討

概要

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Eight cases of peritoneal serous surface papillary carcinoma were clinically evaluated. The mean age was 63.6 years (range, 48 to 84 years). The most common symptom was abdominal fullness. Adenocarcinoma cells were observed in cervical and endometrial smears taken from 4 patients. CT and MRI findings indicated ascites and / or an abnormal tumor with calcification in the pelvic or abdominal cavity. No primary lesions were found in the ovary, the tubes or the uterus at the time of laparotomy. Bulky lesions were found on the peritoneum, omentum, serosa of the bowel and surface of the ovaries. Adenocarcinoma cell clusters were detected in ascites of 8 patients. The measuring of serum CA125 and CA72-4 concentrations may be useful for effective treatment and monitoring of the clinical course of peritoneal serous surface papillary carcinoma. All of the patients were treated with cytoreductive surgery and received cisplatin-based chemotherapy. Four patients with a≦2cm residual tumor are alive. Three of 4 patients who had a>2cm residual tumor died 12 to 18 months after surgery.
社団法人日本産科婦人科学会の論文
2000-03-01