妊娠末期に心不全を呈した周産期心筋症の1例

概要

論文の詳細を見る
Peripartum cardiomyopathy (PPCM) is responsible for 45-75% of maternal deaths, most of which are associated with heart failure. Although many possible causative factors such as viral, autoimmune, genetic and hormonal actions have been considered, the cause of this condition remains unknown. A 29-year-old women presented with PPCM in the late third trimester of gestation. No evidence of heart disease was detected before the pregnancy and the signs and symptoms of heart failure first appeared at 34 weeks of gestation. Preterm stillbirth occurred and induction was followed by vaginal delivery. Immediately after delivery the patient was treated with β-blockers, diuretics, digitalis and anticoagulants. The muscle fibers of her heart showed signs of hypertrophy and scattered round cell infiltrates. On discharge 16 weeks after admission, further reduction of her heart size was noted.
社団法人日本産科婦人科学会の論文
1999-06-01