興味ある妊娠経過をたどった免疫性血小板減少症を伴ったβ_2GPI依存性抗カルジオリピン抗体強陽性, ループスアンチコアグラント陰性の抗リン脂質抗体症候群の1例

概要

論文の詳細を見る
A twenty-five-year-old Japanese woman had a low platelet count (7.3×10^4/μl) pointed out in a blood test in the first trimester. There was avery higher titer (>125U/ml) of β_2-Glycoprotein I-dependent anticardiolipin antibodies and her lowest platelet count was 0.1×10^4/μl. Three times she received high dose γ-globulin therapy, and continuous internal use of steroids, low dose aspirin (aspirin 81 mg) and Saireitoh(Kampo). When she had a cesarean section, her platelet count was 4.3×10^4/μl, and the amount of blood lost during the operation was 310ml. After the operation, we gave her heparin for 3 days, and continued low dose aspirin. Her postoperative clinical course was good. Her newborn infant is 2,060g (AGA), healthy and there are no abnormal findings in the laboratory data. I consider that the diagnosis of this case should be antiphospholipid syndrome with low platelet counts because of clinical course and histological fidings of placenta.
社団法人日本産科婦人科学会の論文
1999-03-01